![]() Since myasthenia gravis symptoms interfere with therapy, patients with GS and their physicians should carefully consider the antibacterial treatment options against disseminated NTM. The patient tested negative for HIV and anti-IFN-γ autoantibodies. Despite multidrug combination therapy, including azithromycin, imipenem/cilastatin, levofloxacin, minocycline, linezolid, and sitafloxacin, the patient ultimately died of the infection. ![]() Bacteremia, spondylitis, intestinal lumber abscess, and lung infection were confirmed by bacteriological examination and diagnostic imaging urinary and intestinal tract infections were suspected by bacteriological examination but not confirmed by imaging. Blood, lumbar tissue, urine, stool, and sputum cultures tested positive for M. Case presentationĪ 57-year-old Japanese male with GS and myasthenia gravis (treated with prednisolone and tacrolimus) was diagnosed with disseminated NTM infection caused by Mycobacterium abscessus subsp. Here, we report a rare case of GS with NTM without HIV or IFN-γ autoantibodies. Although Mycobacterium rarely causes infection in patients with GS, disseminated nontuberculous mycobacterial (NTM) infection frequently occurs in GS patients that are also positive for the human immunodeficiency virus (HIV) or anti-interferon (IFN)-γ autoantibodies. Good’s syndrome (GS) is characterized by immunodeficiency, and can lead to severe infection, which is the most significant complication. ![]()
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